The secret life of ACE2 as a receptor for the SARS virus.
Identifieur interne : 005D39 ( Main/Exploration ); précédent : 005D38; suivant : 005D40The secret life of ACE2 as a receptor for the SARS virus.
Auteurs : Dimiter S. Dimitrov [États-Unis]Source :
- Cell [ 0092-8674 ] ; 2003.
Descripteurs français
- KwdFr :
- MESH :
- métabolisme : Carboxypeptidases, Protéines de fusion virale, Récepteurs de surface cellulaire, Virus du SRAS.
- physiologie : Fusion membranaire, Sites de fixation.
- Conformation des protéines, Peptidyl-Dipeptidase A.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Carboxypeptidases, Receptors, Cell Surface, Viral Fusion Proteins.
- metabolism : SARS Virus.
- physiology : Binding Sites, Membrane Fusion.
- chemical : Peptidyl-Dipeptidase A, Protein Conformation.
Abstract
The membrane-associated carboxypeptidase angiotensin-converting enzyme 2 (ACE2) is an essential regulator of heart function. Now, Li at al. identify and characterize an unexpected second function of ACE2 as a partner of the SARS-CoV spike glycoprotein in mediating virus entry and cell fusion.
DOI: 10.1016/s0092-8674(03)00976-0
PubMed: 14675530
Affiliations:
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Le document en format XML
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Now, Li at al. identify and characterize an unexpected second function of ACE2 as a partner of the SARS-CoV spike glycoprotein in mediating virus entry and cell fusion.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Maryland</li></region></list><tree><country name="États-Unis"><region name="Maryland"><name sortKey="Dimitrov, Dimiter S" sort="Dimitrov, Dimiter S" uniqKey="Dimitrov D" first="Dimiter S" last="Dimitrov">Dimiter S. Dimitrov</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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